A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids

The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.

Chi tiết về thư mục
Những tác giả chính: Willis, M, Piccio, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2002
Miêu tả
Tóm tắt:The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.