A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids

The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.

Bibliographic Details
Main Authors: Willis, M, Piccio, V
Format: Journal article
Language:English
Published: 2002
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author Willis, M
Piccio, V
author_facet Willis, M
Piccio, V
author_sort Willis, M
collection OXFORD
description The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.
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spelling oxford-uuid:4908e7e9-184c-4d5c-a6dd-6967eb3e31bc2022-03-26T15:29:11ZA direct catalytic aldol route to protected beta-hydroxy-alpha-amino acidsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4908e7e9-184c-4d5c-a6dd-6967eb3e31bcEnglishSymplectic Elements at Oxford2002Willis, MPiccio, VThe combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.
spellingShingle Willis, M
Piccio, V
A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title_full A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title_fullStr A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title_full_unstemmed A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title_short A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
title_sort direct catalytic aldol route to protected beta hydroxy alpha amino acids
work_keys_str_mv AT willism adirectcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids
AT picciov adirectcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids
AT willism directcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids
AT picciov directcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids