A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids
The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids.
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2002
|
_version_ | 1797066594162049024 |
---|---|
author | Willis, M Piccio, V |
author_facet | Willis, M Piccio, V |
author_sort | Willis, M |
collection | OXFORD |
description | The combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids. |
first_indexed | 2024-03-06T21:44:18Z |
format | Journal article |
id | oxford-uuid:4908e7e9-184c-4d5c-a6dd-6967eb3e31bc |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T21:44:18Z |
publishDate | 2002 |
record_format | dspace |
spelling | oxford-uuid:4908e7e9-184c-4d5c-a6dd-6967eb3e31bc2022-03-26T15:29:11ZA direct catalytic aldol route to protected beta-hydroxy-alpha-amino acidsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4908e7e9-184c-4d5c-a6dd-6967eb3e31bcEnglishSymplectic Elements at Oxford2002Willis, MPiccio, VThe combination of triethylamine, magnesium(II) perchlorate and bipyridine generates a catalyst system for the efficient combination of ethyl isothiocyanatoacetate and a range of aromatic aldehydes. The products of these reactions are synthetically valuable protected β-hydroxy α-amino acids. |
spellingShingle | Willis, M Piccio, V A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title | A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title_full | A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title_fullStr | A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title_full_unstemmed | A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title_short | A direct catalytic aldol route to protected beta-hydroxy-alpha-amino acids |
title_sort | direct catalytic aldol route to protected beta hydroxy alpha amino acids |
work_keys_str_mv | AT willism adirectcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids AT picciov adirectcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids AT willism directcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids AT picciov directcatalyticaldolroutetoprotectedbetahydroxyalphaaminoacids |