The role and uses of antibodies in COVID-19 infections: a living review

Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are centra...

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Main Authors: Scourfield, DO, Reed, SG, Quastel, M, Alderson, J, Bart, VMT, Teijeira Crespo, A, Jones, R, Pring, E, Richter, FC, Issa, FG, Burnell, SEA
Other Authors: Oxford-Cardiff COVID-19 Literature Consortium
Format: Journal article
Language:English
Published: Oxford University Press 2021
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author Scourfield, DO
Reed, SG
Quastel, M
Alderson, J
Bart, VMT
Teijeira Crespo, A
Jones, R
Pring, E
Richter, FC
Issa, FG
Burnell, SEA
author2 Oxford-Cardiff COVID-19 Literature Consortium
author_facet Oxford-Cardiff COVID-19 Literature Consortium
Scourfield, DO
Reed, SG
Quastel, M
Alderson, J
Bart, VMT
Teijeira Crespo, A
Jones, R
Pring, E
Richter, FC
Issa, FG
Burnell, SEA
author_sort Scourfield, DO
collection OXFORD
description Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.
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spelling oxford-uuid:491d14a8-19a0-4078-9904-ed3932b173842022-03-26T15:29:45ZThe role and uses of antibodies in COVID-19 infections: a living reviewJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:491d14a8-19a0-4078-9904-ed3932b17384EnglishSymplectic ElementsOxford University Press2021Scourfield, DOReed, SGQuastel, MAlderson, JBart, VMTTeijeira Crespo, AJones, RPring, ERichter, FCIssa, FGBurnell, SEAOxford-Cardiff COVID-19 Literature ConsortiumCoronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.
spellingShingle Scourfield, DO
Reed, SG
Quastel, M
Alderson, J
Bart, VMT
Teijeira Crespo, A
Jones, R
Pring, E
Richter, FC
Issa, FG
Burnell, SEA
The role and uses of antibodies in COVID-19 infections: a living review
title The role and uses of antibodies in COVID-19 infections: a living review
title_full The role and uses of antibodies in COVID-19 infections: a living review
title_fullStr The role and uses of antibodies in COVID-19 infections: a living review
title_full_unstemmed The role and uses of antibodies in COVID-19 infections: a living review
title_short The role and uses of antibodies in COVID-19 infections: a living review
title_sort role and uses of antibodies in covid 19 infections a living review
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