HLA heterozygosity contributes to susceptibility to rheumatoid arthritis.

We have investigated the role of HLA-DR genotypes in 184 patients with severe rheumatoid arthritis (RA) and in 46 patients with Felty syndrome, to establish the relative contribution of the RA-associated subtypes of DR4 (Dw4, Dw14, and Dw15). There was an excess of DR4 homozygotes, particularly Dw4/...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Wordsworth, B, Pile, K, Buckely, J, Lanchbury, J, Ollier, B, Lathrop, M, Bell, J
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 1992