Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase
Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalysed reactions. Isotopically-labelled L-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltrans...
| Hauptverfasser: | , , , , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
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