Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalysed reactions. Isotopically-labelled L-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltrans...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Harrison, PJ, Gable, K, Somashekarappa, N, Kelly, V, Clarke, DJ, Naismith, JH, Dunn, TM, Campopiano, DJ
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	American Society for Biochemistry and Molecular Biology 2019

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