Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo.
Accumulation of type I collagen is a key event in renal interstitial fibrosis. As there is no effective treatment, understanding the site where collagen is transcribed and the factors driving it in response to disease in vivo is critical for designing future therapies. The present research investiga...
Main Authors: | Fragiadaki, M, Witherden, A, Kaneko, T, Sonnylal, S, Pusey, C, Bou-Gharios, G, Mason, R |
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Format: | Journal article |
Language: | English |
Published: |
2011
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