Interstitial fibrosis is associated with increased COL1A2 transcription in AA-injured renal tubular epithelial cells in vivo.
Accumulation of type I collagen is a key event in renal interstitial fibrosis. As there is no effective treatment, understanding the site where collagen is transcribed and the factors driving it in response to disease in vivo is critical for designing future therapies. The present research investiga...
Հիմնական հեղինակներ: | Fragiadaki, M, Witherden, A, Kaneko, T, Sonnylal, S, Pusey, C, Bou-Gharios, G, Mason, R |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2011
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Նմանատիպ նյութեր
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High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1.
: Fragiadaki, M, և այլն
Հրապարակվել է: (2011) -
Fibroblast-directed CTGF over-expression in vivo promotes systemic connective tissue fibrosis reminiscent of fibroproliferative diseases
: Sonnylal, S, և այլն
Հրապարակվել է: (2009) -
Norcantharidin inhibits renal interstitial fibrosis by blocking the tubular epithelial-mesenchymal transition.
: Ying Li, և այլն
Հրապարակվել է: (2013-01-01) -
Correction: Norcantharidin Inhibits Renal Interstitial Fibrosis by Blocking the Tubular Epithelial-Mesenchymal Transition
Հրապարակվել է: (2013-01-01) -
Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis
: Hui Yang, և այլն
Հրապարակվել է: (2019-10-01)