Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals

The analysis of circulating tumour DNA (ctDNA) through minimally invasive liquid biopsies is promising for early multi-cancer detection and monitoring minimal residual disease. Most existing methods focus on targeted deep sequencing, but few integrate multiple data modalities. Here, we develop a met...

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Príomhchruthaitheoirí:	Vavoulis, DV, Cutts, A, Thota, N, Brown, J, Sugar, R, Rueda, A, Ardalan, A, Howard, K, Matos Santo, F, Sannasiddappa, T, Miller, B, Ash, S, Liu, Y, Song, C, Nicholson, BD, Dreau, H, Tregidgo, C, Schuh, A
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Nature Research 2025

Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals

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