Rhomboids: 7 years of a new protease family.
Drosophila Rhomboid-1 was discovered to be the first known intramembrane serine protease about 7 years ago. The study of the rhomboid-like family has since blossomed, and the purpose of this review is to take stock of where the field is, and how it may progress in the next few years. Three major the...
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| Format: | Journal article |
| Language: | English |
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2009
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| _version_ | 1826270786723250176 |
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| author | Freeman, M |
| author_facet | Freeman, M |
| author_sort | Freeman, M |
| collection | OXFORD |
| description | Drosophila Rhomboid-1 was discovered to be the first known intramembrane serine protease about 7 years ago. The study of the rhomboid-like family has since blossomed, and the purpose of this review is to take stock of where the field is, and how it may progress in the next few years. Three major themes are the increasing understanding of the biological roles of rhomboids, the detailed information we now have about their function and mechanism, and the promising leads they offer as medical targets. |
| first_indexed | 2024-03-06T21:46:17Z |
| format | Journal article |
| id | oxford-uuid:49b68fd6-5d63-448a-a63d-9a16e0e0c56b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:46:17Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:49b68fd6-5d63-448a-a63d-9a16e0e0c56b2022-03-26T15:33:13ZRhomboids: 7 years of a new protease family.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:49b68fd6-5d63-448a-a63d-9a16e0e0c56bEnglishSymplectic Elements at Oxford2009Freeman, MDrosophila Rhomboid-1 was discovered to be the first known intramembrane serine protease about 7 years ago. The study of the rhomboid-like family has since blossomed, and the purpose of this review is to take stock of where the field is, and how it may progress in the next few years. Three major themes are the increasing understanding of the biological roles of rhomboids, the detailed information we now have about their function and mechanism, and the promising leads they offer as medical targets. |
| spellingShingle | Freeman, M Rhomboids: 7 years of a new protease family. |
| title | Rhomboids: 7 years of a new protease family. |
| title_full | Rhomboids: 7 years of a new protease family. |
| title_fullStr | Rhomboids: 7 years of a new protease family. |
| title_full_unstemmed | Rhomboids: 7 years of a new protease family. |
| title_short | Rhomboids: 7 years of a new protease family. |
| title_sort | rhomboids 7 years of a new protease family |
| work_keys_str_mv | AT freemanm rhomboids7yearsofanewproteasefamily |