Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB.
The cytosine analog 1,3-diaza-2-oxophenothiazine (tC) is a fluorescent nucleotide that forms Watson-Crick base pairs with dG. The Klenow fragment of DNA polymerase I (an A-family polymerase) can efficiently bypass tC on the template strand and incorporate deoxyribose-triphosphate-tC into the growing...
Prif Awduron: | Walsh, J, Bouamaied, I, Brown, T, Wilhelmsson, L, Beuning, P |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2011
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Eitemau Tebyg
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