Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB.

Discrimination against the cytosine analog tC by Escherichia coli DNA polymerase IV DinB.

The cytosine analog 1,3-diaza-2-oxophenothiazine (tC) is a fluorescent nucleotide that forms Watson-Crick base pairs with dG. The Klenow fragment of DNA polymerase I (an A-family polymerase) can efficiently bypass tC on the template strand and incorporate deoxyribose-triphosphate-tC into the growing...

Bibliografski detalji
Glavni autori:	Walsh, J, Bouamaied, I, Brown, T, Wilhelmsson, L, Beuning, P
Format:	Journal article
Jezik:	English
Izdano:	2011

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