The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction.

The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction.

High-affinity, high-selectivity protein-protein interactions that are critical for cell survival present an evolutionary paradox: How does selectivity evolve when acquired mutations risk a lethal loss of high-affinity binding? A detailed understanding of selectivity in such complexes requires struct...

Bibliografiset tiedot
Päätekijät:	Meenan, N, Sharma, A, Fleishman, S, Macdonald, C, Morel, B, Boetzel, R, Moore, G, Baker, D, Kleanthous, K
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2010

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