Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane.
(Figure Presented) Selective digestion: α-Chymotrypsin was used to synthesize a cyclodextrin azo dye rotaxane and to digest it back to its components. E → Z photoisomerization of the rotaxane completely changes its affinity for the enzyme. The presence of the cyclodextrin accelerates digestion of th...
| Egile Nagusiak: | , , , |
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| Formatua: | Journal article |
| Hizkuntza: | English |
| Argitaratua: |
2006
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| _version_ | 1826270811519975424 |
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| author | Cheetham, A Hutchings, MG Claridge, T Anderson, H |
| author_facet | Cheetham, A Hutchings, MG Claridge, T Anderson, H |
| author_sort | Cheetham, A |
| collection | OXFORD |
| description | (Figure Presented) Selective digestion: α-Chymotrypsin was used to synthesize a cyclodextrin azo dye rotaxane and to digest it back to its components. E → Z photoisomerization of the rotaxane completely changes its affinity for the enzyme. The presence of the cyclodextrin accelerates digestion of the E isomer and prevents that of the Z isomer. © 2006 Wiley-VCH Verlag GmbH and Co. KGaA. |
| first_indexed | 2024-03-06T21:46:42Z |
| format | Journal article |
| id | oxford-uuid:49d58e45-bc3b-40b1-927b-89460cf91bb6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:46:42Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:49d58e45-bc3b-40b1-927b-89460cf91bb62022-03-26T15:34:07ZEnzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:49d58e45-bc3b-40b1-927b-89460cf91bb6EnglishSymplectic Elements at Oxford2006Cheetham, AHutchings, MGClaridge, TAnderson, H(Figure Presented) Selective digestion: α-Chymotrypsin was used to synthesize a cyclodextrin azo dye rotaxane and to digest it back to its components. E → Z photoisomerization of the rotaxane completely changes its affinity for the enzyme. The presence of the cyclodextrin accelerates digestion of the E isomer and prevents that of the Z isomer. © 2006 Wiley-VCH Verlag GmbH and Co. KGaA. |
| spellingShingle | Cheetham, A Hutchings, MG Claridge, T Anderson, H Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title | Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title_full | Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title_fullStr | Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title_full_unstemmed | Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title_short | Enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide-linked rotaxane. |
| title_sort | enzymatic synthesis and photoswitchable enzymatic cleavage of a peptide linked rotaxane |
| work_keys_str_mv | AT cheethama enzymaticsynthesisandphotoswitchableenzymaticcleavageofapeptidelinkedrotaxane AT hutchingsmg enzymaticsynthesisandphotoswitchableenzymaticcleavageofapeptidelinkedrotaxane AT claridget enzymaticsynthesisandphotoswitchableenzymaticcleavageofapeptidelinkedrotaxane AT andersonh enzymaticsynthesisandphotoswitchableenzymaticcleavageofapeptidelinkedrotaxane |