Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.

FOXP2 mutation causes a severe inherited speech and language defect, while the related transcription factors FOXP1, FOXP3 and FOXP4 are implicated in cancer. FOXP2 mRNA and protein expression were characterised in normal human tissues, haematological cell lines and multiple myeloma (MM) patients...

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Autors principals: Campbell, A, Lyne, L, Brown, P, Launchbury, R, Bignone, P, Chi, J, Roncador, G, Lawrie, C, Gatter, K, Kusec, R, Banham, A
Format: Journal article
Idioma:English
Publicat: 2010