Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis
<strong>Objectives</strong> To critically appraise and evaluate the diagnostic value of symptoms and signs in identifying UTI in older adult outpatients, using evidence from observational studies. <strong>Methods</strong> We searched Medline and Medline in process, Embase an...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
2018
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| _version_ | 1797066864100114432 |
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| author | Gbinigie, OA Ordonez-Mena, JM Fanshawe, TR Pluddemann, A Heneghan, C |
| author_facet | Gbinigie, OA Ordonez-Mena, JM Fanshawe, TR Pluddemann, A Heneghan, C |
| author_sort | Gbinigie, OA |
| collection | OXFORD |
| description | <strong>Objectives</strong> To critically appraise and evaluate the diagnostic value of symptoms and signs in identifying UTI in older adult outpatients, using evidence from observational studies. <strong>Methods</strong> We searched Medline and Medline in process, Embase and Web of Science, from inception up to September 2017. We included studies assessing the diagnostic accuracy of symptoms and/or signs in predicting UTI in outpatients aged 65 years and above. Study quality was assessed using the QUADAS-2 tool. <strong>Results</strong> We identified 15 eligible studies of variable quality, with a total of 12,039 participants (range 65–4259), and assessed the diagnostic accuracy of 66 different symptoms and signs in predicting UTI. A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients. Inability to perform a number of acts of daily living were predictors of UTI: For example, disability in feeding oneself, + ve LR: 11.8 (95% CI 5.51–25.2) and disability in washing one's hands and face, + ve LR: 6.84 (95% CI 4.08–11.5). <strong>Conclusions</strong> The limited evidence of varying quality shows that a number of symptoms and signs traditionally associated with UTI may have limited diagnostic value in older adult outpatients. |
| first_indexed | 2024-03-06T21:48:07Z |
| format | Journal article |
| id | oxford-uuid:4a50916d-4014-4596-9e01-baf9b52f23cb |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:48:07Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:4a50916d-4014-4596-9e01-baf9b52f23cb2022-03-26T15:36:50ZDiagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4a50916d-4014-4596-9e01-baf9b52f23cbEnglishSymplectic Elements at OxfordElsevier2018Gbinigie, OAOrdonez-Mena, JMFanshawe, TRPluddemann, AHeneghan, C<strong>Objectives</strong> To critically appraise and evaluate the diagnostic value of symptoms and signs in identifying UTI in older adult outpatients, using evidence from observational studies. <strong>Methods</strong> We searched Medline and Medline in process, Embase and Web of Science, from inception up to September 2017. We included studies assessing the diagnostic accuracy of symptoms and/or signs in predicting UTI in outpatients aged 65 years and above. Study quality was assessed using the QUADAS-2 tool. <strong>Results</strong> We identified 15 eligible studies of variable quality, with a total of 12,039 participants (range 65–4259), and assessed the diagnostic accuracy of 66 different symptoms and signs in predicting UTI. A number of symptoms and signs typically associated with UTI, such as nocturia, urgency and abnormal vital signs, were of limited use in older adult outpatients. Inability to perform a number of acts of daily living were predictors of UTI: For example, disability in feeding oneself, + ve LR: 11.8 (95% CI 5.51–25.2) and disability in washing one's hands and face, + ve LR: 6.84 (95% CI 4.08–11.5). <strong>Conclusions</strong> The limited evidence of varying quality shows that a number of symptoms and signs traditionally associated with UTI may have limited diagnostic value in older adult outpatients. |
| spellingShingle | Gbinigie, OA Ordonez-Mena, JM Fanshawe, TR Pluddemann, A Heneghan, C Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title | Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title_full | Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title_fullStr | Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title_full_unstemmed | Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title_short | Diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients: systematic review and meta-analysis |
| title_sort | diagnostic value of symptoms and signs for identifying urinary tract infection in older adult outpatients systematic review and meta analysis |
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