Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis.

Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis.

OBJECTIVE: Mediation of RNA interference by oligonucleotides constitutes a powerful approach for the silencing of genes involved in the pathogenesis of inflammatory disease, but in vivo application of this technique requires effective delivery to immune cells and/or sites of inflammation. The aim o...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Andreakos, E, Rauchhaus, U, Stavropoulos, A, Endert, G, Wendisch, V, Benahmed, A, Giaglis, S, Karras, J, Lee, S, Gaus, H, Bennett, C, Williams, R, Sideras, P, Panzner, S
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2009

Eitemau Tebyg

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