Exploring the fold space preferences of ancient and newborn protein superfamilies

Exploring the fold space preferences of ancient and newborn protein superfamilies

<p>Protein evolution is a complex and diverse process, yielding an incredible assortment of biological functions and pathways occurring in the cells of living organisms. The way in which a protein's structure is constrained by its functional role and its notable conservation across even d...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Edwards, H, Hannah Edwards
Andre forfattere:	Deane, C
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Mathematical genetics and bioinformatics (statistics) Protein folding Mathematical biology Bioinformatics (life sciences) Life Sciences

Lignende værker

Protein fold evolution on completed genomes: distinguishing between young and old folds
af: Abeln, S, et al.
Udgivet: (2007)

Fold recognition and alignment in the ‘twilight zone’
af: Hill, J, et al.
Udgivet: (2013)

Gene x gene interactions in genome wide association studies
af: Bhattacharya, K
Udgivet: (2014)

An integrated genomic approach for the identification and analysis of single nucleotide polymorphisms that affect cancer in humans
af: Repapi, E
Udgivet: (2013)

The estimation of recombination rates from population genetic data
af: Auton, A
Udgivet: (2007)

Statistical challenges in the detection of mutation and variation using high throughput sequencing
af: Pfeifer, S
Udgivet: (2012)

A method for the identification of biological pathways
af: Honti, F
Udgivet: (2014)

Application of the Neutral Indel Model to genome sequences for diverse metazoans
af: Meader, S
Udgivet: (2010)

Design and analysis of genome-wide association studies
af: Barrett, J
Udgivet: (2008)

Large-scale genetic analysis of quantitative traits
af: Randall, J, et al.
Udgivet: (2012)

The evolutionary dynamics of neutral networks: lessons from RNA
af: Rendel, M
Udgivet: (2008)

On genetic variants underlying common disease
af: Hechter, E
Udgivet: (2011)

Statistical HLA type imputation from large and heterogeneous datasets
af: Dilthey, A
Udgivet: (2012)

Cotranslational protein folding - fact or fiction?
af: Deane, C, et al.
Udgivet: (2007)

Imputation aided analysis of the association between autoimmune diseases and the MHC
af: Moutsianas, L
Udgivet: (2011)

Modelling sequential protein folding under kinetic control
af: Huard, F, et al.
Udgivet: (2006)

Germline determinants of 5-fluorouracil drug toxicity and patient survival in colorectal cancer
af: Rosmarin, DN
Udgivet: (2013)

Multiple sequence analysis in the presence of alignment uncertainty
af: Herman, J, et al.
Udgivet: (2014)

Multilocus sequence analysis of the pathogen Neisseria meningitidis
af: Wilson, D
Udgivet: (2005)

Comparative neurotranscriptomics in mammals and birds
af: Belgard, TG
Udgivet: (2011)

Statistical models for single-cell data
af: Pierson, E
Udgivet: (2015)

Protein loop structure prediction
af: Choi, Y
Udgivet: (2011)

Medical relevance and functional consequences of protein truncating variants
af: Rivas Cruz, M
Udgivet: (2015)

Inferring the fine-scale structure and evolution of recombination from high-throughput genome sequencing
af: Venn, O
Udgivet: (2013)

Genes contributing to variation in fear-related behaviour
af: Krohn, J, et al.
Udgivet: (2013)

Modelling and comparing protein interaction networks using subgraph counts
af: Chegancas Rito, TM
Udgivet: (2012)

DifFUZZY: a novel clustering algorithm for systems biology
af: Cominetti Allende, O, et al.
Udgivet: (2012)

Fine-mapping complex traits in heterogeneous stock rats
af: Baud, A
Udgivet: (2013)

NucleoFinder: a statistical approach for the detection of nucleosome positions
af: Becker, J, et al.
Udgivet: (2013)

Genetics of ankylosing spondylitis
af: Karaderi, T
Udgivet: (2012)

Statistical methods for mapping complex traits
af: Allchin, L
Udgivet: (2014)

Statistical methods for genotype microarray data on large cohorts of individuals
af: O'Connell, JM
Udgivet: (2014)

The detection, structure and uses of extended haplotype identity in population genetic data
af: Xifara, DK
Udgivet: (2014)

Statistical methods for the analysis of genetic association studies
af: Su, Z
Udgivet: (2008)

Bayesian methods for fine mapping in genetic association studies
af: Frangou, E
Udgivet: (2013)

LD-based SNP and genotype calling from next-generation sequencing reads.
af: Menelaou, A
Udgivet: (2012)

Probabilistic models of RNA secondary structure
af: Anderson, JWJ
Udgivet: (2013)

Genome annotation and selectional analysis of viral evolution
af: de Groot, S
Udgivet: (2008)

Comparative analysis of derived mutations across human populations.
af: Feder, A, et al.
Udgivet: (2013)

Selection along the HIV-1 genome through the CTL mediated immune response
af: Palmer, D
Udgivet: (2014)