A functional polymorphism of the stromelysin gene (MMP-3) influences susceptibility to primary sclerosing cholangitis.
BACKGROUND AND AIMS: We have investigated the influence of a biallelic polymorphism of the promoter region of stromelysin (matrix metalloproteinase 3) on susceptibility to primary sclerosing cholangitis (PSC). The 5A allele is associated with increased transcription, compared with wild-type (6A). ME...
Prif Awduron: | , , , , , , , , , , |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2001
|