Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis

<p style="text-align:justify;"> <b>Background:</b> Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. The MHC class II transactivator (MHC2TA) is the master controller o...

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Bibliographic Details
Main Authors: Ramagopalan, S, Dyment, D, Morrison, K, Herrera, B, Deluca, G, Lincoln, MR, Orton, S, Handunnetthi, L, Chao, M, Sadovnick, A, Ebers, G
Format: Journal article
Language:English
Published: BioMed Central 2008