Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.

Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.

Sex differences in schizophrenia are well known, but their genetic basis has not been identified. We performed a genome-wide association scan for schizophrenia in an Ashkenazi Jewish population using DNA pooling. We found a female-specific association with rs7341475, a SNP in the fourth intron of th...

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Main Authors: Shifman, S, Johannesson, M, Bronstein, M, Chen, S, Collier, D, Craddock, N, Kendler, K, Li, T, O'Donovan, M, O'Neill, F, Owen, M, Walsh, D, Weinberger, DR, Sun, C, Flint, J, Darvasi, A
格式: Journal article
语言:English
出版: 2008

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