Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women.

Sex differences in schizophrenia are well known, but their genetic basis has not been identified. We performed a genome-wide association scan for schizophrenia in an Ashkenazi Jewish population using DNA pooling. We found a female-specific association with rs7341475, a SNP in the fourth intron of th...

Descripció completa

Dades bibliogràfiques
Autors principals: Shifman, S, Johannesson, M, Bronstein, M, Chen, S, Collier, D, Craddock, N, Kendler, K, Li, T, O'Donovan, M, O'Neill, F, Owen, M, Walsh, D, Weinberger, DR, Sun, C, Flint, J, Darvasi, A
Format: Journal article
Idioma:English
Publicat: 2008