Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection.

Improving the outcome of bone marrow transplantation by using CD52 monoclonal antibodies to prevent graft-versus-host disease and graft rejection.

Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity after allogeneic bone marrow transplantation, but can be avoided by removing T lymphocytes from the donor bone marrow. However, T-cell depletion increases the risk of graft rejection. This study examined the use of CD52 mon...

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Hlavní autoři: Hale, G, Zhang, M, Bunjes, D, Prentice, H, Spence, D, Horowitz, M, Barrett, A, Waldmann, H
Médium: Journal article
Jazyk:English
Vydáno: 1998

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