Radiosynthesis of [18F]ArylSCF2H using aryl boronic acids, S-(chlorofluoromethyl)benzenesulfonothioate and [18F]fluoride
Herein, we report a mild and practical protocol for the copper-catalyzed chlorofluoromethylthiolation of (hetero)aryl boronic acids with the novel reagent PhSO2SCFClH. The resulting products are amenable to halogen exchange 18F-fluorination with cyclotron-produced [18F]fluoride affording [18F]ArSCF2...
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| Hlavní autoři: |
Zhao, Q,
Isenegger, PG,
Wilson, TC,
Sap, JBI,
Guibbal, F,
Lu, L,
Gouverneur, V,
Shen, Q |
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| Médium: | Journal article
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| Jazyk: | English |
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| Vydáno: |
Chinese Chemical Society
2020
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