Bluetongue virus VP4 is an RNA-capping assembly line.

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assembl...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Sutton, G, Grimes, J, Stuart, D, Roy, P
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2007
विवरण
सारांश:Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.