Polyinosinic acid is a ligand for toll-like receptor 3.

Innate immune responses are critical in controlling viral infections. Viral proteins and nucleic acids have been shown to be recognized by pattern recognition receptors of the Toll-like receptor (TLR) family, triggering downstream signaling cascades that lead to cellular activation and cytokine prod...

Full description

Bibliographic Details
Main Authors: Marshall-Clarke, S, Downes, J, Haga, I, Bowie, A, Borrow, P, Pennock, J, Grencis, R, Rothwell, P
Format: Journal article
Language:English
Published: 2007