Activation of latent protease function of pro-hK2, but not pro-PSA, involves autoprocessing.

BACKGROUND: Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of an extensive kallikrein family of proteases. Both proteases are secreted as zymogens or proenzymes containing a seven amino acid propeptide that must be proteolytically removed for enzymatic activation....

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Denmeade, SR, Lövgren, J, Khan, SR, Lilja, H, Isaacs, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2001