The linear ubiquitin assembly complex’s recruitment to signaling complexes: The role of HOIP’s zinc finger domains

The linear ubiquitin assembly complex’s recruitment to signaling complexes: The role of HOIP’s zinc finger domains

The linear ubiquitin chain assembly complex (LUBAC) regulates NF-κB activation and prevents cell death by conjugating M1 polyubiquitin on inflammatory complexes through its catalytic subunit HOIP. Although the conjugation of M1 chains is well described, less is known about the mechanism of LUBAC’s r...

书目详细资料
主要作者:	Nathanail, E
其他作者:	Elliott, P
格式:	Thesis
语言:	English
出版:	2021
主题:	Structural biology Biochemistry Biophysics

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