Genotype-specific MRD interpretation improves stratification in paediatric acute lymphoblastic leukaemia
<strong>Purpose</strong> Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy...
المؤلفون الرئيسيون: | O'Connor, D, Enshaei, A, Bartram, J, Hancock, J, Harrison, C, Hough, R, Samarasinghe, S, Schwab, C, Vora, A, Wade, R, Moppett, J, Moorman, A, Goulden, N |
---|---|
التنسيق: | Journal article |
منشور في: |
American Society of Clinical Oncology
2017
|
مواد مشابهة
-
Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MRD) clearance in childhood acute lymphoblastic leukaemia (ALL)
حسب: Moorman, A, وآخرون
منشور في: (2007) -
Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.
حسب: O'Connor, D, وآخرون
منشور في: (2017) -
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia.
حسب: Moorman, A, وآخرون
منشور في: (2014) -
Post-Remission MRD Kinetics in Children with Acute Lymphoblastic Leukaemia Receiving Augmented BFM Consolidation Compared with Other Regimens Results of the Medical Research Council Trial UKALL2003.
حسب: Cutting, R, وآخرون
منشور في: (2008) -
Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol.
حسب: Patrick, K, وآخرون
منشور في: (2014)