Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.

Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.

A series of small molecule orally bioavailable ghrelin receptor agonists have been identified through systematic optimisation of a high throughput screening hit.

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Hlavní autoři: Witherington, J, Abberley, L, Briggs, M, Collis, K, Dean, D, Gaiba, A, King, N, Kraus, H, Shuker, N, Steadman, J, Takle, A, Sanger, G, Wadsworth, G, Butler, S, McKay, F, Muir, A, Winborn, K, Heightman, T
Médium: Journal article
Jazyk:English
Vydáno: 2008

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