Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation.
A series of small molecule orally bioavailable ghrelin receptor agonists have been identified through systematic optimisation of a high throughput screening hit.
Glavni autori: | Witherington, J, Abberley, L, Briggs, M, Collis, K, Dean, D, Gaiba, A, King, N, Kraus, H, Shuker, N, Steadman, J, Takle, A, Sanger, G, Wadsworth, G, Butler, S, McKay, F, Muir, A, Winborn, K, Heightman, T |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2008
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Potent achiral agonists of the ghrelin (growth hormone secretagogue) receptor. Part I: Lead identification.
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