Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study.

Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study.

Most adults with acute lymphoblastic leukemia (ALL) who achieve complete remission (CR) will relapse. We examined the outcome of 609 adults with recurring ALL, all of whom were previously treated on the Medical Research Council (MRC) UKALL12/ECOG2993 study, where the overall survival (OS) of newly d...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Fielding, A, Richards, S, Chopra, R, Lazarus, H, Litzow, MR, Buck, G, Durrant, I, Luger, S, Marks, D, Franklin, I, McMillan, A, Tallman, MS, Rowe, J, Goldstone, A
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2007

Míreanna comhchosúla

Outcomes in older adults with acute lymphoblastic leukaemia (ALL): results from the international MRC UKALL XII/ECOG2993 trial.
de réir: Sive, J, et al.
Foilsithe / Cruthaithe: (2012)

Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993.
de réir: Lazarus, H, et al.
Foilsithe / Cruthaithe: (2006)

Adult patients with acute lymphoblastic leukaemia (ALL) who relapse have a dismal outlook: Results from MRC UKALL XII/ECOG 2993 trial.
de réir: Chopra, R, et al.
Foilsithe / Cruthaithe: (2003)

Induction therapy for adults with acute lymphoblastic leukemia (ALL): Results of nearly 1,400 patients from the international ALL trial (MRC UKALL XII/ECOG E2993).
de réir: Rowe, J, et al.
Foilsithe / Cruthaithe: (2003)

Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993.
de réir: Rowe, J, et al.
Foilsithe / Cruthaithe: (2005)

Standard Consolidation/Maintenance Chemotherapy Is Consistently Superior to a Single Autologous Transplant for Adult Patients with Acute Lymphoblastic Leukemia: Results of the International ALL Trial (MRC UKALL XII/ECOG E2993).
de réir: Rowe, J, et al.
Foilsithe / Cruthaithe: (2008)

The outcome of 551 1(st) CR transplants in adult ALL from the UKALL XII/ECOG 2993 study
de réir: Goldstone, A, et al.
Foilsithe / Cruthaithe: (2004)

Adult patients with acute lymphoblastic leukemia (ALL) and central nervous system (CNS) leukemia at diagnosis may attain durable complete remissions (CR). Results from the international ALL trial (MRC UKALL-XII/ECOG E2993)
de réir: Lazarus, H, et al.
Foilsithe / Cruthaithe: (2004)

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993).
de réir: Marks, D, et al.
Foilsithe / Cruthaithe: (2009)

Imatinib Significantly Enhances Long-Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia; Final Results of the UKALLXII/ECOG2993 Trial
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2010)

Imatinib Significantly Enhances Long Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia, Final Results of the UKALLXII/ECOG2993 Trial
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2010)

Imatinib Significantly Enhances Long Term Outcomes In Philadelphia Positive Acute Lymphoblastic Leukaemia, Final Results of the UKALLXII/ECOG2993 Trial
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2010)

Philadelphia chromosome plus ve patients with adult acute lymphoblastic leukaemia (ALL), early results from the international ALL trial (MRC UKALL-XII/ECOG E2993).
de réir: Goldstone, A, et al.
Foilsithe / Cruthaithe: (1999)

In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993).
de réir: Goldstone, A, et al.
Foilsithe / Cruthaithe: (2008)

Does imatinib change the outcome in philapdelphia chromosome positive acute lympooblastic leukaemia in adults? Data from the UKALLXII/ECOG2993 study
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2007)

Delays in Post-Remission Chemotherapy for Philadelphia Chromosome Negative Acute Lymphoblastic Leukemia are Associated with Inferior Outcomes in Patients who Undergo Allogeneic Transplant: An Analysis from ECOG 2993/MRC UK ALLXII.
de réir: Kumar, A, et al.
Foilsithe / Cruthaithe: (2016)

At three years, patients with acute lymphoblastic leukaemia are still at risk for relapse. Results of the international MRC UKALLXII/ECOG E2993 trial
de réir: Ganzel, C, et al.
Foilsithe / Cruthaithe: (2020)

The outcome of 267 Philadelphia positive adults in the international UKALL12/ECOG E 2993 study. Final analysis and the role of allogeneic transplant in those under 50 years.
de réir: Goldstone, A, et al.
Foilsithe / Cruthaithe: (2003)

Prospective outcome data on 267 unselected adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia confirms superiority of allogeneic transplantation over chemotherapy in the pre-imatinib era: results from the International ALL Trial MRC UKALLXII/ECOG2993.
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2009)

UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia.
de réir: Fielding, A, et al.
Foilsithe / Cruthaithe: (2014)

Favorable results of allogeneic bone marrow transplantation (BMT) for adults with Philadelphia (Ph)-chromosome-negative acute lymphoblastic leukemia (ALL) in first complete remission (CR): Results from the International ALL trial (MRC UKALL XII/ECOG E2993).
de réir: Rowe, J, et al.
Foilsithe / Cruthaithe: (2001)

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL) Results From the International MRC/ECOG Trial
de réir: Sive, J, et al.
Foilsithe / Cruthaithe: (2010)

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL) Results From the International MRC/ECOG Trial
de réir: Sive, J, et al.
Foilsithe / Cruthaithe: (2010)

Inability to Tolerate Standard Therapy Is a Major Reason for Poor Outcome In Older Adults with Acute Lymphoblastic Leukemia (ALL): Results From the International MRC/ECOG Trial
de réir: Sive, J, et al.
Foilsithe / Cruthaithe: (2010)

The impact of imatinib therapy on adult Philadelphia positive acute lymphoblastic leukaemia (ALL): Early results from the UKALL12/ECOG 2993 study
de réir: Patel, B, et al.
Foilsithe / Cruthaithe: (2005)

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukaemia (ALL): Analysis of cytogenetic data from 1,235 patients on the medical research council (MRC) UKALLXII/Eastern cooperative oncology group (ECOG) 2993 trial.
de réir: Moorman, A, et al.
Foilsithe / Cruthaithe: (2005)

Allogeneic transplant (related or unrelated donor) is the preferred treatment for adult Philadelphia chromosome positive (Ph plus) acute lymphoblastic leukaemia (ALL). Results from the international ALL trial (MRC UKALLXII/ECOG E2993).
de réir: Goldstone, A, et al.
Foilsithe / Cruthaithe: (2001)

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol.
de réir: Mansour, MR, et al.
Foilsithe / Cruthaithe: (2009)

Implications for the Use of Monoclonal Antibodies in Future Adult ALL Trials: Analysis of Antigen Expression in 505 B-Lineage (B-Lin) ALL Patients (pts) on the MRC UKALLXII/ECOG2993 Intergroup Trial.
de réir: Paietta, E, et al.
Foilsithe / Cruthaithe: (2008)

Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993.
de réir: Patel, B, et al.
Foilsithe / Cruthaithe: (2010)

Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial.
de réir: Moorman, A, et al.
Foilsithe / Cruthaithe: (2007)

Minimal residual disease is a significant predictor of treatment failure in B lineage adult ALL: final results of the international trial UKALL XII:ECOG 2993
de réir: Patel, B, et al.
Foilsithe / Cruthaithe: (2009)

The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial
de réir: David I. Marks, et al.
Foilsithe / Cruthaithe: (2013-06-01)

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lymphoblastic Leukemia (B-ALL) Patients (pts) From the International UKALLXII/E2993 Trial: No Difference In Results Between B Cell Immunophenotypic Subgroups
de réir: Lrrzow, MR, et al.
Foilsithe / Cruthaithe: (2010)

Clinical effect of Imatinib following remission induction in adult Philadelphia chromosome-positive acute lymphoblastic leukaemia: early results from the MRC UKALL12 Study
de réir: Patel, B, et al.
Foilsithe / Cruthaithe: (2006)

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lyrnphoblastic Leukemia (B ALL) Patients (pts) From the International UKALLXII/E2993 Trial No Difference In Results Between B Cell Immuno phenotypic Subgroups
de réir: Lrrzow, MR, et al.
Foilsithe / Cruthaithe: (2010)

Outcome of 1,229 Adult Philadelphia Chromosome Negative B Acute Lyrnphoblastic Leukemia (B ALL) Patients (pts) From the International UKALLXII/E2993 Trial No Difference In Results Between B Cell Immuno phenotypic Subgroups
de réir: Lrrzow, MR, et al.
Foilsithe / Cruthaithe: (2010)

The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL X and XA compared: a report from the MRC Paediatric and Adult Working Parties.
de réir: Chessells, J, et al.
Foilsithe / Cruthaithe: (1998)

Unlike Paediatric T-ALL, Notch-1 and FBXW7 Mutations Do Not Seem to Predict a Better Outcome in Adult Patients: Data from the UKALLXII/ECOG2993 Protocol.
de réir: Mansour, MR, et al.
Foilsithe / Cruthaithe: (2008)

Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA. MRC Adult Leukaemia Working Party.
de réir: Secker-Walker, L, et al.
Foilsithe / Cruthaithe: (1997)