High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.
RATIONALE: T-cell responses have been implicated in control and exacerbation of lung injury during influenza A virus (IAV) infection. OBJECTIVES: To examine the breadth and magnitude of influenza-specific CD4(+) and CD8(+) T-cell responses during acute phase of infection. METHODS: Influenza-specific...
Main Authors: | Zhao, Y, Zhang, Y, Denney, L, Young, D, Powell, T, Peng, Y, Li, N, Yan, H, Wang, D, Shu, Y, Kendrick, Y, Mcmichael, A, Ho, L, Dong, T |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2012
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