High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.

High levels of virus-specific CD4+ T cells predict severe pandemic influenza A virus infection.

RATIONALE: T-cell responses have been implicated in control and exacerbation of lung injury during influenza A virus (IAV) infection. OBJECTIVES: To examine the breadth and magnitude of influenza-specific CD4(+) and CD8(+) T-cell responses during acute phase of infection. METHODS: Influenza-specific...

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Hlavní autoři: Zhao, Y, Zhang, Y, Denney, L, Young, D, Powell, T, Peng, Y, Li, N, Yan, H, Wang, D, Shu, Y, Kendrick, Y, Mcmichael, A, Ho, L, Dong, T
Médium: Journal article
Jazyk:English
Vydáno: 2012

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