The oscillation of mitotic kinase governs cell cycle latches in mammalian cells
The mammalian cell cycle alternates between two phases: S-G2-M with high levels of A- and B-type cyclin-dependent kinases (CycA,B:CDK); and G1 with persistent degradation of CycA,B by Cdh1-activated APC/C (anaphase promoting complex/cyclosome). Because CDKs phosphorylate and inactivate Cdh1, these t...
Main Authors: | Dragoi, C-M, Kaur, E, Barr, AR, Tyson, JJ, Novak, B |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Company of Biologists
2024
|
Similar Items
-
The oscillation of mitotic kinase governs cell cycle latches in mammalian cells
by: Dragoi, C-M, et al.
Published: (2023) -
Mitotic kinase oscillation governs the latching of cell cycle switches
by: Novak, B, et al.
Published: (2022) -
A “latching-gate” model of progression through the eukaryotic cell cycle
by: Tyson, JJ, et al.
Published: (2024) -
Robust mitotic entry is ensured by a latching switch
by: Chloe Tuck, et al.
Published: (2013-07-01) -
Mitotic exit in mammalian cells.
by: Kapuy, O, et al.
Published: (2009)