OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.
Conjugation of Met1-linked polyubiquitin (Met1-Ub) by the linear ubiquitin chain assembly complex (LUBAC) is an important regulatory modification in innate immune signaling. So far, only few Met1-Ub substrates have been described, and the regulatory mechanisms have remained elusive. We recently iden...
Үндсэн зохиолчид: | Fiil, B, Damgaard, R, Wagner, SA, Keusekotten, K, Fritsch, M, Bekker-Jensen, S, Mailand, N, Choudhary, C, Komander, D, Gyrd-Hansen, M |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2013
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