OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.

Conjugation of Met1-linked polyubiquitin (Met1-Ub) by the linear ubiquitin chain assembly complex (LUBAC) is an important regulatory modification in innate immune signaling. So far, only few Met1-Ub substrates have been described, and the regulatory mechanisms have remained elusive. We recently iden...

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Detalhes bibliográficos
Principais autores:	Fiil, B, Damgaard, R, Wagner, SA, Keusekotten, K, Fritsch, M, Bekker-Jensen, S, Mailand, N, Choudhary, C, Komander, D, Gyrd-Hansen, M
Formato:	Journal article
Idioma:	English
Publicado em:	2013

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