Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London

Adult necrotising enterocolitis secondary Clostridium perfringens type C-pig-bel disease-is rarely seen outside of Pacific populations, with the highest incidence being in Papau New Guinea. We present the first reported case of pig-bel disease in a previously well patient without diabetes following...

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Main Authors: Wormald, J, Dindyal, S, Mellor, F, Behar, N
Format: Journal article
Language:English
Published: BMJ Publishing Group 2016
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author Wormald, J
Dindyal, S
Mellor, F
Behar, N
author_facet Wormald, J
Dindyal, S
Mellor, F
Behar, N
author_sort Wormald, J
collection OXFORD
description Adult necrotising enterocolitis secondary Clostridium perfringens type C-pig-bel disease-is rarely seen outside of Pacific populations, with the highest incidence being in Papau New Guinea. We present the first reported case of pig-bel disease in a previously well patient without diabetes following food poisoning since 1996. In this case, the enterotoxin-induced disease necessitated emergency laparotomy and bowel resection following the failure of medical treatment and worsening septic shock. We hypothesise that obstruction secondary to a sigmoid diverticular stricture complicated by infection-related oedema led to colonic stasis and rapid progression of disease and bowel loss. Following bowel resection, several parenteral antibiotic agents and prolonged intensive care, this patient survived this severe infective process and was discharged home.
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spelling oxford-uuid:4b38cea5-9864-4973-8c6c-dc927b320a6e2022-03-26T15:42:18ZAdult necrotising enterocolitis-pig-bel disease: a Pacific disease in LondonJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4b38cea5-9864-4973-8c6c-dc927b320a6eEnglishSymplectic Elements at OxfordBMJ Publishing Group2016Wormald, JDindyal, SMellor, FBehar, NAdult necrotising enterocolitis secondary Clostridium perfringens type C-pig-bel disease-is rarely seen outside of Pacific populations, with the highest incidence being in Papau New Guinea. We present the first reported case of pig-bel disease in a previously well patient without diabetes following food poisoning since 1996. In this case, the enterotoxin-induced disease necessitated emergency laparotomy and bowel resection following the failure of medical treatment and worsening septic shock. We hypothesise that obstruction secondary to a sigmoid diverticular stricture complicated by infection-related oedema led to colonic stasis and rapid progression of disease and bowel loss. Following bowel resection, several parenteral antibiotic agents and prolonged intensive care, this patient survived this severe infective process and was discharged home.
spellingShingle Wormald, J
Dindyal, S
Mellor, F
Behar, N
Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title_full Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title_fullStr Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title_full_unstemmed Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title_short Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London
title_sort adult necrotising enterocolitis pig bel disease a pacific disease in london
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AT dindyals adultnecrotisingenterocolitispigbeldiseaseapacificdiseaseinlondon
AT mellorf adultnecrotisingenterocolitispigbeldiseaseapacificdiseaseinlondon
AT beharn adultnecrotisingenterocolitispigbeldiseaseapacificdiseaseinlondon