Carbohydrate and domain architecture of an immature antibody glycoform exhibiting enhanced effector functions.

Antibodies contain a conserved glycosylation site that has emerged as a target for the modulation of antibody effector functions. The crystal structure of a biosynthetic intermediate of human IgG1, bearing immature oligomannose-type glycans and reported to display increased antibody-dependent cellul...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Crispin, M, Bowden, T, Coles, C, Harlos, K, Aricescu, A, Harvey, D, Stuart, D, Jones, E
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2009