Transcriptional promiscuity of the human alpha-globin gene.
The human alpha-globin gene displays the unusual property of transcriptional promiscuity: that is, it functions in the absence of an enhancer when transfected into nonerythroid cell lines. It is also unusual in that its promoter region lies in a hypomethylated HpaII tiny fragment (HTF) island contai...
Main Authors: | Whitelaw, E, Hogben, P, Hanscombe, O, Proudfoot, N |
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Format: | Journal article |
Language: | English |
Published: |
1989
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