Cytoskeletal protein degradation in brain death donor kidneys associates with adverse posttransplant outcomes
In brain death, cerebral injury contributes to systemic biological dysregulation, causing significant cellular stress in donor kidneys adversely impacting the quality of grafts. Here, we hypothesized that donation after brain death (DBD) kidneys undergo proteolytic processes that may deem grafts sus...
Main Authors: | Vaughan, RH, Kresse, J-C, Farmer, LK, Thézénas, ML, Kessler, BM, Lindeman, JHN, Sharples, EJ, Welsh, GI, Nørregaard, R, Ploeg, RJ, Kaisar, ME |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Wiley
2022
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