Inborn and acquired metabolic defects in cancer.
The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. However, the subsequent identification of oncogenes and tumor suppressor genes has displaced Warburg's theory pointing towards genetic aberrations as the underlining cause o...
Main Authors: | Frezza, C, Pollard, P, Gottlieb, E |
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Format: | Journal article |
Language: | English |
Published: |
2011
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