Genomic epidemiology of artemisinin resistant malaria.

The current epidemic of artemisinin resistant Plasmodium falciparum in Southeast Asia is the result of a soft selective sweep involving at least 20 independent kelch13 mutations. In a large global survey, we find that kelch13 mutations which cause resistance in Southeast Asia are present at low freq...

Full description

Bibliographic Details
Main Authors: MalariaGEN Plasmodium falciparum Community Project, Miotto, O, Woodrow, C, Almagro-Garcia, J, Sinha, I, Ashley, E, Boni, M, Bull, P, Day, N, Dolecek, C, Dondorp, A, Fanello, C, Newton, P, Nosten, F, Price, R, White, N, Cornelius, V, Giacomantonio, R, Henrichs, C, Pearson, R, McVean, G, Rockett, K, Miles, A, Jeffery, B, Kwiatkowski, D
Format: Journal article
Language:English
Published: eLife Sciences 2016

Similar Items