Interleukin-23 drives intestinal inflammation through direct activity on T cells.

Mutations in the IL23R gene are linked to inflammatory bowel disease susceptibility. Experimental models have shown that interleukin-23 (IL-23) orchestrates innate and T cell-dependent colitis; however, the cell populations it acts on to induce intestinal immune pathology are unknown. Here, using Il...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Ahern, P, Schiering, C, Buonocore, S, McGeachy, M, Cua, D, Maloy, K, Powrie, F
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2010