DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?

Our current understanding of cancer suggests that every tumour has individual features. Approaches to cancer treatment require thorough comprehension of the mechanisms triggering genomic instability and protecting cancer cells from therapeutic treatments. Base excision repair (BER) is a frontline DN...

Podrobná bibliografie
Hlavní autoři:	Poletto, M, Legrand, A, Dianov, G
Médium:	Journal article
Jazyk:	English
Vydáno:	Bentham Science Publishers 2017

Podobné jednotky

p53 coordinates base excision repair to prevent genomic instability
Autor: Poletto, M, a další
Vydáno: (2016)

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
Autor: Poletto, M, a další
Vydáno: (2017)

DNA repair fidelity of base excision repair pathways in human cell extracts.
Autor: Zhang, Q, a další
Vydáno: (2005)

Regulation of the base excision repair pathway
Autor: Fletcher, S, a další
Vydáno: (2017)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
Autor: Parsons, J, a další
Vydáno: (2004)

Russia and the Kuriles : Achilles’ Heel or Bargaining Chip?
Autor: Cheang, Chris
Vydáno: (2019)

Base excision repair targets for cancer therapy.
Autor: Dianov, G
Vydáno: (2011)

Monitoring base excision repair by in vitro assays.
Autor: Dianov, G
Vydáno: (2003)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
Autor: Sleeth, K, a další
Vydáno: (2004)

Base excision repair fidelity in normal and cancer cells.
Autor: Chan, K, a další
Vydáno: (2006)

In vitro base excision repair using mammalian cell extracts.
Autor: Parsons, J, a další
Vydáno: (2012)

Non-compliance: the Achilles' heel of anti-fracture efficacy.
Autor: Seeman, E, a další
Vydáno: (2007)

Mammalian base excision repair: the forgotten archangel.
Autor: Dianov, G, a další
Vydáno: (2013)

Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
Autor: Chen, X, a další
Vydáno: (2018)

Buying consent: the Achilles' heel of aid-induced community participation
Autor: Bano, M
Vydáno: (2017)

Achilles Heel or, How to Win an Election without Really Trying.
Autor: Collier, P, a další
Vydáno: (2009)

Co-ordination of base excision repair and genome stability.
Autor: Parsons, J, a další
Vydáno: (2013)

Targeting base excision repair to improve cancer therapies.
Autor: Sharma, R, a další
Vydáno: (2007)

Targeting the Achilles heel of mosquito-borne viruses for antiviral therapy
Autor: Jackman, Joshua A., a další
Vydáno: (2021)

Amirah's recurring injury may prove to be her achilles' heel
Autor: Singh, Aftar
Vydáno: (2013)

The emerging role of Mule and ARF in the regulation of base excision repair.
Autor: Khoronenkova, S, a další
Vydáno: (2011)

The emerging role of Mule and ARF in the regulation of base excision repair
Autor: Khoronenkova, S, a další
Vydáno: (2011)

Achilles' heel of sociality revealed by energetic poverty trap in cursorial hunters
Autor: Rasmussen, G, a další
Vydáno: (2008)

Isolation of a small molecule inhibitor of DNA base excision repair.
Autor: Madhusudan, S, a další
Vydáno: (2005)

Democracy’s Achilles Heel or, How to Win an Election without Really Trying.
Autor: Collier, P, a další
Vydáno: (2009)

Democracy's Achilles heel or, how to win an election without really trying
Autor: Hoeffler, A, a další
Vydáno: (2009)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
Autor: Parsons, J, a další
Vydáno: (2005)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
Autor: Dianova, I, a další
Vydáno: (2004)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
Autor: Allinson, S, a další
Vydáno: (2004)

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Autor: Yang, J, a další
Vydáno: (2010)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
Autor: Parsons, J, a další
Vydáno: (2008)

The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition
Autor: Feng, Yu-xiong, a další
Vydáno: (2018)

Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
Autor: Chan, K, a další
Vydáno: (2007)

Base excision repair of radiation-induced DNA damage in mammalian cells
Autor: Cooper, S, a další
Vydáno: (2013)

Overcoming therapeutic inertia as the achilles heel for improving suboptimal diabetes care: An integrative review
Autor: Chew, Boon-How, a další
Vydáno: (2023)

Functional DNA repair capacity assays : a focus on base excision repair
Autor: Chaim, Isaac Alexander
Vydáno: (2016)

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability
Autor: Markkanen, E, a další
Vydáno: (2015)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
Autor: Parsons, J, a další
Vydáno: (2011)

Targeting the viral Achilles' heel: Recognition of 5'-triphosphate RNA in innate anti-viral defence
Autor: Rehwinkel, J, a další
Vydáno: (2013)

Targeting the viral Achilles' heel: recognition of 5'-triphosphate RNA in innate anti-viral defence.
Autor: Rehwinkel, J, a další
Vydáno: (2013)