Longitudinal prostate-specific antigen reference ranges: Choosing the underlying model of age-related changes

Longitudinal prostate-specific antigen reference ranges: Choosing the underlying model of age-related changes

Serial measurements of prostate-specific antigen (PSA) are used as a biomarker for men diagnosed with prostate cancer following an active monitoring programme. Distinguishing pathological changes from natural age-related changes is not straightforward. Here, we compare four approaches to modelling a...

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Bibliographic Details
Main Authors:	Simpkin, A, Metcalfe, C, Martin, R, Lane, J, Donovan, J, Hamdy, F, Neal, D, Tilling, K
Format:	Journal article
Language:	English
Published:	SAGE Publications 2013

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