Signature-tagged mutagenesis: barcoding mutants for genome-wide screens.

DNA signature tags (molecular barcodes) facilitate functional screens by identifying mutants in mixed populations that have a reduced or increased adaptation to a particular environment. Many innovative adaptations and refinements in the technology have been described since its original use with Sal...

Descrizione completa

Dettagli Bibliografici
Autori principali: Mazurkiewicz, P, Tang, C, Boone, C, Holden, D
Natura: Journal article
Lingua:English
Pubblicazione: 2006