Signature-tagged mutagenesis: barcoding mutants for genome-wide screens.

DNA signature tags (molecular barcodes) facilitate functional screens by identifying mutants in mixed populations that have a reduced or increased adaptation to a particular environment. Many innovative adaptations and refinements in the technology have been described since its original use with Sal...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Mazurkiewicz, P, Tang, C, Boone, C, Holden, D
Format: Journal article
Sprog:English
Udgivet: 2006