Signature-tagged mutagenesis: barcoding mutants for genome-wide screens.
DNA signature tags (molecular barcodes) facilitate functional screens by identifying mutants in mixed populations that have a reduced or increased adaptation to a particular environment. Many innovative adaptations and refinements in the technology have been described since its original use with Sal...
Main Authors: | , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado: |
2006
|