Differences in the biologic activity of 2 novel MEK inhibitors revealed by 18F-FDG PET: analysis of imaging data from 2 phase I trials.

Differences in the biologic activity of 2 novel MEK inhibitors revealed by 18F-FDG PET: analysis of imaging data from 2 phase I trials.

UNLABELLED: Two mitogen-activated protein kinase kinase (MAPK2, also known as MEK) inhibitors were assessed with (18)F-FDG PET in separate phase I clinical studies, clearly illustrating the potential of metabolic imaging for dose, dosing regimen, and compound selection in early-phase trials and uti...

Podrobná bibliografie
Hlavní autoři:	Kraeber-Bodéré, F, Carlier, T, Naegelen, V, Shochat, E, Lumbroso, J, Trampal, C, Nagarajah, J, Chua, S, Hugonnet, F, Stokkel, M, Gleeson, F, Tessier, J
Médium:	Journal article
Jazyk:	English
Vydáno:	2012

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